Scientific Research

Angel Program (NCT04462185): A Prospective Cohort Study of Chinese Patients With Pulmonary Nodules: Prediction of Lung Cancer Using Noninvasive Biomarkers
Project profile

The Angel Program is a prospective observational study led by Academician Nanshan Zhong, AnchorDx and Lung Cancer Initiative (LCI) with six clinical centers participating. The study aims to recruit 3,000 patients with indeterminate pulmonary nodules (IPNs) sized in 5-30 mm. These patients will be followed up for 2-3 years. The clinical information, blood samples, CT imaging DICOM data, and pathological result of each participant will be collected at each visit. The purpose of this study is to validate the clinical, imaging and molecular biomarkers in lung cancers from IPN patients, and further improve the diagnostic efficiency of patients with IPNs.

This study has obtained approval from the Human Genetic Resources Administration of China (HGRAC), and was launched in August 2020. 

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